SCHEMBL6704764

SCHEMBL6704764

CS(=O)(=O)ON=C(C#N)c1cccs1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.39
NPC1 O15118 6/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
DAO P14920 1/20 0.37
PKM P14618 4/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 4/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 3/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
HDAC1 Q13547 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
CTSL P07711 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6704762 1.00 RAB9A (0.39) RAB9ANPC1CES2CES1DAO
SCHEMBL2259958 0.86 ALDH1A1 (0.37) RAB9ANPC1CES2CES1DAO
SCHEMBL2259960 0.86 ALDH1A1 (0.37) RAB9ANPC1CES2CES1DAO
SCHEMBL7050654 0.83 DAO (0.37) RAB9ANPC1CES2CES1DAO
SCHEMBL385065 0.83 MAPT (0.43) RAB9ANPC1CES2CES1DAO
SCHEMBL385064 0.83 MAPT (0.43) RAB9ANPC1CES2CES1DAO
SCHEMBL6704979 0.83 DAO (0.37) RAB9ANPC1CES2CES1DAO
SCHEMBL1397229 0.83 ALDH1A1 (0.46) RAB9ANPC1PKMMAPTKMT2A
SCHEMBL1397231 0.83 ALDH1A1 (0.46) RAB9ANPC1PKMMAPTKMT2A
SCHEMBL6705023 0.82 HDAC3 (0.38) RAB9ANPC1PKMMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity DIETLIKER KURT (CH) 2004-01-22 US claimed
EP-0925529-B1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SC HOLDING AG (CH) 2003-04-16 EP claimed
CN-107809996-A Multistage method caused by nitric oxide BSN医疗有限公司 2018-03-16 CN disclosed
CN-107708647-A Medical Bathing Equipment BSN医疗有限公司 2018-02-16 CN disclosed
US-6770420-B2 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity CIBA SPECIALTY CHEMICALS CORPORATION 2004-08-03 US disclosed
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity DIETLIKER KURT (CH) 2004-01-22 US disclosed
EP-0925529-B1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SC HOLDING AG (CH) 2003-04-16 EP disclosed
EP-0925529-A1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY Ciba SC Holding AG (CH) 1999-06-30 EP disclosed
WO-1998010335-A1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity SULT1E1, CCNT1, CCNE1 RAB9A 4672/4885NPC1 4796/4885CES2 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.