Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYAB | P02511 | 2/20 | 0.48 |
| ▸ | CRYAA | P02489 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706905 | 0.94 | CRYAB (0.48) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL7710063 | 0.87 | USP2 (0.62) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL9332046 | 0.84 | CRYAB (0.48) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL2510047 | 0.83 | CDC25A (0.53) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL6406909 | 0.83 | CDC25A (0.53) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL23457921 | 0.83 | CDC25A (0.53) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL25035253 | 0.83 | CDC25A (0.53) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL1955815 | 0.83 | CDC25A (0.53) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL13770890 | 0.83 | CDC25A (0.53) | CRYABCRYAAUSP2ALDH1A1LMNA | |
| SCHEMBL9331755 | 0.81 | CRYAB (0.47) | CRYABCRYAAUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048838-A1 | Meiosis regulating compounds | GRONVALD FREDERIK CHRISTIAN (DK) | 2004-03-11 | — | — | US | disclosed |
| US-6645953-B2 | Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, for regulating meiosis in oocytes and in male germ cells; use in treating infertility, | NOVO NORDISK A/S (DK) | 2003-11-11 | — | — | US | disclosed |
| US-20020013302-A1 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013302-A1 | Meiosis regulating compounds | CYP11A1, NR5A1, MNS1 | CRYAB 1240/4885CRYAA 2434/4885USP2 4073/4885 |
| US-20040048838-A1 | Meiosis regulating compounds | CYP11A1, NR5A1, MNS1 | CRYAB 1240/4885CRYAA 2434/4885USP2 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.