Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6314424 | 0.88 | CYP3A4 (0.33) | CA1 | |
| SCHEMBL7718260 | 0.81 | CA2 (0.45) | CA2CA1GRIK1GRIK2ACE2 | |
| SCHEMBL3823555 | 0.81 | CA2 (0.45) | CA2CA1GRIK1GRIK2ACE2 | |
| SCHEMBL3827255 | 0.81 | CA2 (0.45) | CA2CA1GRIK1GRIK2ACE2 | |
| SCHEMBL8692682 | 0.80 | CA2 (0.47) | CA2CA1ACE2GPR84FFAR1 | |
| SCHEMBL97487 | 0.77 | CA2 (0.41) | CA2CA1ACE2GPR84FFAR1 | |
| SCHEMBL7752126 | 0.77 | CA2 (0.41) | CA2CA1ACE2GPR84FFAR1 | |
| SCHEMBL98813 | 0.77 | CA2 (0.41) | CA2CA1ACE2GPR84FFAR1 | |
| SCHEMBL97027 | 0.77 | CA2 (0.41) | CA2CA1GRIK1GRIK2ACE2 | |
| SCHEMBL7747690 | 0.77 | CA2 (0.41) | CA2CA1ACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9224540-B2 | Conductive polymer for solid electrolyte capacitor | SOLVAY USA, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| EP-2855554-A2 | CONDUCTIVE POLYMER FOR SOLID ELECTROLYTIC CAPACITOR | Solvay USA Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| US-20140014881-A1 | CONDUCTIVE POLYMER FOR SOLID ELECTROLYTE CAPACITOR | PLEXTRONICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| WO-2013181165-A2 | CONDUCTIVE POLYMER FOR SOLID ELECTROLYTIC CAPACITOR | PLEXTRONICS, INC. (US) | 2013-12-05 | — | — | WO | disclosed |
| US-20040034042-A1 | Preservative composition | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034042-A1 | Preservative composition | XDH, XPA, SORBS1 | CA2 48/4885CA1 162/4885GRIK1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.