SCHEMBL6705171

SCHEMBL6705171

O=C(c1ccc(Cl)cc1)N1CCN(c2ccccc2)CC1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.88
ALDH1A1 P00352 1/20 0.88
POLB P06746 2/20 0.74
MEN1 O00255 1/20 0.74
KMT2A Q03164 1/20 0.74
SLC6A7 Q99884 1/20 0.74
HSP90AA1 P07900 1/20 0.73
AKR1C3 P42330 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.68
TSHR P16473 2/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
USP2 O75604 1/20 0.67
MAPT P10636 1/20 0.67
MAPK1 P28482 1/20 0.67
HSD17B10 Q99714 1/20 0.65
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA7 P43166 1/20 0.65
CA9 Q16790 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24158074 0.92 LMNA (0.85) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL10721777 0.92 MEN1 (0.87) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL8595777 0.88 POLB (0.87) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL8161635 0.85 SLC6A7 (1.00) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL1711137 0.85 LMNA (0.64) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL9321490 0.84 LMNA (0.74) LMNAALDH1A1POLBHSP90AA1AKR1C3
SCHEMBL10722382 0.84 POLB (0.81) LMNAALDH1A1POLBKMT2AHSP90AA1
SCHEMBL9585721 0.84 POLB (0.81) LMNAALDH1A1POLBKMT2AHSP90AA1
SCHEMBL3276407 0.84 MEN1 (0.74) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL1711050 0.84 MEN1 (0.74) LMNAALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
US-20040145562-A1 Electrophoretic display and process for producing the same CANON KABUSHIKI KAISHA (JP) 2004-07-29 US disclosed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed