Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 12/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590425 | 0.88 | LMNA (0.46) | LRRK2ALDH1A1CCNA2CDK2CNR2 | |
| SCHEMBL14626137 | 0.85 | ALDH1A1 (0.54) | ALDH1A1PDE4BCCNA2CDK2 | |
| SCHEMBL14590424 | 0.80 | CNR2 (0.46) | LRRK2JAK2CNR2 | |
| SCHEMBL14067291 | 0.79 | CAMK1D (0.47) | LRRK2JAK2ALDH1A1CNR2 | |
| SCHEMBL14590427 | 0.77 | ALDH1A1 (0.53) | LRRK2JAK2ALDH1A1 | |
| SCHEMBL24885934 | 0.75 | RAB9A (0.50) | ALDH1A1 | |
| SCHEMBL16370470 | 0.75 | MEN1 (0.49) | ALDH1A1 | |
| SCHEMBL6705299 | 0.74 | STAT6 (0.45) | PDE4BCCNA2CDK2 | |
| SCHEMBL16446157 | 0.74 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL6691958 | 0.73 | STAT6 (0.46) | PDE4BCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |