Urea

Urea

SCHEMBL670545

N=C=N.NC(N)=O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL30336008 0.86 LMNA (0.55)
Urea SCHEMBL5915116 0.86
Urea SCHEMBL10965886 0.86 LMNA (0.55)
Urea SCHEMBL2288083 0.86 LMNA (0.55)
Urea SCHEMBL27583568 0.82
Urea SCHEMBL8517667 0.82
Urea SCHEMBL411583 0.78
Urea SCHEMBL7756359 0.78 LMNA (1.00)
Urea SCHEMBL20641124 0.78 LMNA (1.00)
Urea C 13 SCHEMBL12476878 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104768955-A Improved process for the acylation of maytansinol IMMUNOGEN INC 2015-07-08 CN claimed
WO-2014053873-A1 POLYMERIC PRODRUG CONJUGATES Piramal Enterprises Limited (IN) 2014-04-10 WO claimed
CN-118005913-A Block copolymer with cell membrane pore-forming property and preparation method and application thereof 四川大学 2024-05-10 CN disclosed
CN-115406979-B High performance liquid chromatography analysis method for residual 1-ethyl [3- (dimethylamino) -propyl ] -carbodiimide hydrochloride 陕西慧康生物科技有限责任公司 2024-02-27 CN disclosed
US-20230374320-A1 METHOD OF PREPARING AN AQUEOUS TITANIUM DIOXIDE SLURRY, THE THUS PRODUCED SLURRY AND COATING COMPOSITIONS CONTAINING THE SAME BASF COATINGS GMBH (DE) 2023-11-23 US disclosed
US-20230365833-A1 AQUEOUS, LOW SOLIDS BASECOAT COMPOSITIONS BASF COATINGS GMBH (DE) 2023-11-16 US disclosed
EP-4225848-A1 METHOD OF PREPARING AN AQUEOUS TITANIUM DIOXIDE SLURRY, THE THUS PRODUCED SLURRY AND COATING COMPOSITIONS CONTAINING THE SAME BASF Coatings GmbH (DE) 2023-08-16 EP disclosed
EP-4217426-A1 AQUEOUS, LOW SOLIDS BASECOAT COMPOSITIONS BASF Coatings GmbH (DE) 2023-08-02 EP disclosed
CN-116368203-A Process for preparing aqueous titanium dioxide slurries, slurries produced thereby and coating compositions containing same 巴斯夫涂料有限公司 2023-06-30 CN disclosed
CN-116323823-A Aqueous low solids basecoat compositions 巴斯夫涂料有限公司 2023-06-23 CN disclosed
CN-115406979-A High performance liquid chromatography analysis method for residual 1-ethyl [3- (dimethylamino) -propyl ] -carbodiimide hydrochloride 陕西慧康生物科技有限责任公司 2022-11-29 CN disclosed
US-6780897-B1 COATING MATERIALS, ADHESIVES OR SEALING COMPOUNDS WHICH CAN BE CROSSLINKED THERMALLY AND/OR WITH ACTINIC RADIATION BASF COATING AG (DE) 2004-08-24 US disclosed
US-6777090-B2 ONE COMPONENT SYSTEM WHERE BINDER AND CROSSLINKER AVOID PREMATURE CROSSLINKING DUE TO ABSENCE OF ISOCYANATE REACTIVE GROUPS; ADHESIVES, COATINGS, SEALANTS; ISOCYANATE, ACID, AND EPOXIDE REACTIVE GROUPS; CARBAMATE GROUPS BASF COATINGS AG (DE) 2004-08-17 US disclosed
US-20030185991-A1 Aqueous coating material, especially aqueous filler or protective base against stones WIGGER GEORGE (DE) 2003-10-02 US disclosed
US-6620511-B1 Comprising water-dispersible hydroxy-functional binder containing urethane groups, a water-dispersible binder containing urethane groups and blocked isocyanate groups, amino resin, optionally, a hydroxy-functional polyester BASF COATINGS AG (DE) 2003-09-16 US disclosed
US-20030091833-A1 Substance mixture which can be cured thermally and by using actinic radiation,and the use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2003-05-15 US disclosed
EP-0438230-B1 Indole-substituted five-membered heteroaromatic compounds MERCK SHARP & DOHME (GB) 1997-04-23 EP disclosed
US-5317103-A Migraine treatment MERCK SHARP & DOHME LIMITED (GB) 1994-05-31 US disclosed
EP-0438230-A2 Indole-substituted five-membered heteroaromatic compounds MERCK SHARP &amp; DOHME LTD. (GB) 1991-07-24 EP disclosed
US-4588525-A Prodrug compounds for dermal application MOLECULAR BIOSYSTEMS, INC. (US) 1986-05-13 US disclosed