⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216469 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL515134 | 0.74 | — | — | |
| SCHEMBL3432560 | 0.74 | — | — | |
| SCHEMBL8657130 | 0.72 | — | — | |
| Hydrazinecarboxamide SCHEMBL1906712 | 0.69 | TSHR (0.50) | — | |
| SCHEMBL4936929 | 0.67 | — | — | |
| SCHEMBL690665 | 0.65 | LMNA (0.44) | — | |
| SCHEMBL690664 | 0.65 | LMNA (0.44) | — | |
| SCHEMBL364147 | 0.63 | — | — | |
| Carbimide SCHEMBL10692895 | 0.63 | CRBN (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112831023-B | High-stability 1, 5-naphthalene diisocyanate and polyurethane elastomer prepared from same | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-112831023-A | High-stability 1, 5-naphthalene diisocyanate and polyurethane elastomer prepared from same | 万华化学集团股份有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-104768955-A | Improved process for the acylation of maytansinol | IMMUNOGEN INC | 2015-07-08 | — | — | CN | claimed |
| WO-2014053873-A1 | POLYMERIC PRODRUG CONJUGATES | Piramal Enterprises Limited (IN) | 2014-04-10 | — | — | WO | claimed |
| CN-118005913-A | Block copolymer with cell membrane pore-forming property and preparation method and application thereof | 四川大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-115406979-B | High performance liquid chromatography analysis method for residual 1-ethyl [3- (dimethylamino) -propyl ] -carbodiimide hydrochloride | 陕西慧康生物科技有限责任公司 | 2024-02-27 | — | — | CN | disclosed |
| US-20230374320-A1 | METHOD OF PREPARING AN AQUEOUS TITANIUM DIOXIDE SLURRY, THE THUS PRODUCED SLURRY AND COATING COMPOSITIONS CONTAINING THE SAME | BASF COATINGS GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230365833-A1 | AQUEOUS, LOW SOLIDS BASECOAT COMPOSITIONS | BASF COATINGS GMBH (DE) | 2023-11-16 | — | — | US | disclosed |
| EP-4225848-A1 | METHOD OF PREPARING AN AQUEOUS TITANIUM DIOXIDE SLURRY, THE THUS PRODUCED SLURRY AND COATING COMPOSITIONS CONTAINING THE SAME | BASF Coatings GmbH (DE) | 2023-08-16 | — | — | EP | disclosed |
| EP-4217426-A1 | AQUEOUS, LOW SOLIDS BASECOAT COMPOSITIONS | BASF Coatings GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| CN-116368203-A | Process for preparing aqueous titanium dioxide slurries, slurries produced thereby and coating compositions containing same | 巴斯夫涂料有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116323823-A | Aqueous low solids basecoat compositions | 巴斯夫涂料有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-6777090-B2 | ONE COMPONENT SYSTEM WHERE BINDER AND CROSSLINKER AVOID PREMATURE CROSSLINKING DUE TO ABSENCE OF ISOCYANATE REACTIVE GROUPS; ADHESIVES, COATINGS, SEALANTS; ISOCYANATE, ACID, AND EPOXIDE REACTIVE GROUPS; CARBAMATE GROUPS | BASF COATINGS AG (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030185991-A1 | Aqueous coating material, especially aqueous filler or protective base against stones | WIGGER GEORGE (DE) | 2003-10-02 | — | — | US | disclosed |
| US-6620511-B1 | Comprising water-dispersible hydroxy-functional binder containing urethane groups, a water-dispersible binder containing urethane groups and blocked isocyanate groups, amino resin, optionally, a hydroxy-functional polyester | BASF COATINGS AG (DE) | 2003-09-16 | — | — | US | disclosed |
| US-20030091833-A1 | Substance mixture which can be cured thermally and by using actinic radiation,and the use thereof | BASF COATINGS AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | US | disclosed |
| EP-0438230-B1 | Indole-substituted five-membered heteroaromatic compounds | MERCK SHARP & DOHME (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5317103-A | Migraine treatment | MERCK SHARP & DOHME LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| EP-0438230-A2 | Indole-substituted five-membered heteroaromatic compounds | MERCK SHARP & DOHME LTD. (GB) | 1991-07-24 | — | — | EP | disclosed |
| US-4588525-A | Prodrug compounds for dermal application | MOLECULAR BIOSYSTEMS, INC. (US) | 1986-05-13 | — | — | US | disclosed |