Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765178 | 0.79 | CYP1A2 (0.46) | CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL7723280 | 0.79 | ACHE (0.41) | ACHELMNARELACYP3A4TSHR | |
| SCHEMBL21881722 | 0.78 | ACHE (0.52) | ACHELMNARELACYP3A4TSHR | |
| SCHEMBL16455125 | 0.71 | ACHE (0.37) | ACHELMNARELACYP3A4TSHR | |
| SCHEMBL25990683 | 0.70 | ACHE (0.50) | ACHELMNARELACYP3A4TSHR | |
| SCHEMBL28847935 | 0.68 | CYP3A4 (0.60) | RELACYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL12241652 | 0.68 | CYP3A4 (0.60) | RELACYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL24043825 | 0.68 | ALDH1A1 (0.50) | ACHELMNACYP3A4TSHRMEN1 | |
| SCHEMBL28462523 | 0.68 | ACHE (0.52) | ACHELMNARELACYP3A4TSHR | |
| SCHEMBL7521294 | 0.67 | ACHE (0.46) | ACHELMNACYP3A4TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101597-A2 | METHODS FOR THE REDUCTION OF DISULFIDE BONDS | FRUTAROM LTD. (IL) | 2004-11-25 | — | — | WO | disclosed |