Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222847 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TSHRGAAEPHX1POLB | |
| SCHEMBL3872340 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CHRM1CYP2D6NPC1RAB9A | |
| SCHEMBL3868712 | 0.82 | MCHR1 (0.55) | ALDH1A1HDAC4HDAC1CHRM1CYP2D6 | |
| SCHEMBL3869095 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HDAC4HDAC1CHRM1POLB | |
| SCHEMBL3870571 | 0.81 | MCHR1 (0.55) | ALDH1A1HDAC4HDAC1CHRM1CYP2D6 | |
| SCHEMBL3870885 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CHRM1CYP2D6NPC1RAB9A | |
| SCHEMBL3870079 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CHRM1CYP2D6NPC1RAB9A | |
| SCHEMBL3873969 | 0.81 | MCHR1 (0.55) | ALDH1A1HDAC4HDAC1CHRM1CYP2D6 | |
| SCHEMBL3870988 | 0.81 | TAAR1 (0.44) | ALDH1A1HDAC4HDAC1TSHRCHRM2 | |
| SCHEMBL3868850 | 0.80 | NPC1 (0.48) | ALDH1A1HDAC4HDAC1CHRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | OPRM1 49/4885OPRD1 46/4885OPRK1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.