SCHEMBL670610

SCHEMBL670610

C#Cc1ccc(CCC)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.45
LIPG Q9Y5X9 2/20 0.45
CA2 P00918 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
ACACB O00763 3/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MGLL Q99685 1/20 0.39
PLK1 P53350 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
THRB P10828 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL31124595 0.98 LPL (0.43) LPLLIPGCA2MAOAMAOB
SCHEMBL9332671 0.94 TSHR (0.49) LPLLIPGCA2MAOAMAOB
SCHEMBL712627 0.86 HSD17B10 (0.50) LPLLIPGCA2TSHRHSD17B10
SCHEMBL21514119 0.85 PLK1 (0.50) ACACBPLK1CNR2THRB
SCHEMBL5179689 0.85 HDAC8 (0.43) CA2MAOAMAOBHDAC8
SCHEMBL170113 0.85 HSD17B10 (0.58) LPLLIPGCA2TSHRHSD17B10
SCHEMBL31403397 0.85 HSD17B10 (0.49) LPLLIPGCA2TSHRHSD17B10
SCHEMBL947879 0.83 HSD17B10 (0.61) LPLLIPGTSHRHSD17B10MGLL
SCHEMBL948801 0.83 HSD17B10 (0.61) LPLLIPGTSHRHSD17B10MGLL
SCHEMBL4745509 0.83 HSD17B10 (0.61) LPLLIPGTSHRHSD17B10MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119633864-A Method for preparing thiophene compound by using one-pot method through double-function catalyst and catalyst used by same 浙江大学 2025-03-18 CN claimed
WO-2025049824-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
CN-117047118-A Method for preparing gold nanowire with adjustable diameter by using alkynyl ligand 南京工业大学 2023-11-14 CN claimed
CN-116237081-A Wrapped Pd-Ni bimetallic catalyst, catalyst preparation method and application 东南大学 2023-06-09 CN claimed
CN-114507121-B Preparation method and product of alpha-alkenyl-alpha, alpha-difluoro aryl ketone compound 南京工业大学 2023-05-26 CN claimed
CN-113149927-B Vanillin isoxazole compound and preparation method and application thereof 北京农学院 2022-10-28 CN claimed
CN-110818537-B One-pot synthesis method of phenoxyeneyne ether compound 西南大学 2022-10-11 CN claimed
CN-114874088-A Acetylenic acid and preparation method thereof 中国科学院上海高等研究院 2022-08-09 CN claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-2341104-B1 Polycarbonate resin composition with excellent scratch resistance and impact strength CHEIL IND INC (KR) 2014-11-12 EP claimed
EP-2582409-B1 HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS NOVARTIS AG (CH) 2014-09-10 EP claimed
EP-2199342-B1 Polylactic acid/polycarbonate resin composition and molded product made using the same CHEIL IND INC (KR) 2014-07-30 EP claimed
EP-2268709-B1 SCRATCH RESISTANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2013-10-02 EP claimed
EP-2222786-B1 SCRATCH-RESISTANT FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION WITH IMPROVED COMPATIBILITY CHEIL IND INC (KR) 2013-01-02 EP claimed
EP-2204412-B1 Polycarbonate resin composition with improved scratch resistance and melt flow index CHEIL IND INC (KR) 2012-08-29 EP claimed
EP-2225325-B1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS ALCON INC (CH) 2011-06-01 EP claimed
EP-1664855-B1 PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS BAUSCH & LOMB (US) 2009-03-11 EP claimed
EP-1177227-B1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORP (US) 2003-10-01 EP claimed
EP-0914169-B1 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LAB INC (US) 2003-07-30 EP claimed