Sugi Predict

Sugi Predict / Compounds / SCHEMBL948801

SCHEMBL948801

SCHEMBL948801

C#Cc1ccc(CCCCCCC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.61
▸ TSHR P16473 1/20 0.61
▸ ESR1 P03372 2/20 0.57
▸ ADRA2A P08913 2/20 0.57
▸ ADORA3 P0DMS8 2/20 0.57
▸ TACR2 P21452 2/20 0.57
▸ SLC6A2 P23975 2/20 0.57
▸ SLC6A4 P31645 2/20 0.57
▸ SLC6A3 Q01959 2/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ KDM4E B2RXH2 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ SHBG P04278 1/20 0.57
▸ TP53 P04637 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ HSPD1 P10809 1/20 0.57
▸ ADRB3 P13945 1/20 0.57
▸ HTR2C P28335 1/20 0.57
▸ HSPE1 P61604 1/20 0.57
▸ HIF1A Q16665 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4745509 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL28243501 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL28242843 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL7794684 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL177025 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL947879 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL31415597 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL2773891 1.00 HSD17B10 (0.61) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL170113 0.98 HSD17B10 (0.58) HSD17B10TSHRESR1ADRA2AADORA3
SCHEMBL10984815 0.94 HSD17B10 (0.70) HSD17B10TSHRESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684182-A Liquid crystal compound with diphenylacetylene skeleton and related liquid crystal composition 西安近代化学研究所 2025-03-25 — — CN disclosed
CN-105646528-B A kind of solubility thiophthene derivative and its preparation and application 中国中化股份有限公司 2018-09-28 — — CN disclosed
US-20160244476-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2016-08-25 — — US disclosed
US-9351970-B2 Anti-viral pyrimidine nucleoside analogues REGA FOUNDATION (BE) 2016-05-31 — — US disclosed
US-20140011764-A1 Anti-Viral Pyrimidine Nucleoside Analogues UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2014-01-09 — — US disclosed
US-8551965-B2 Anti-viral pyrimidine nucleoside analogues UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2013-10-08 — — US disclosed
US-20110015147-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2011-01-20 — — US disclosed
US-7820631-B2 Anti-viral pyrimidine nucleoside analogues REGA FOUNDATION (BE) 2010-10-26 — — US disclosed
US-7329896-B2 Polymerizable charge transport compounds MERCK PATENT GMBH (DE) 2008-02-12 — — US disclosed
EP-1404683-B1 POLYMERISABLE CHARGE TRANSPORT COMPOUNDS MERCK PATENT GMBH (DE) 2005-10-05 — — EP disclosed
US-6800763-B2 FOR USE AS SEMICONDUCTOR CHARGE TRANSPORT MATERIALS, IN OPTICAL, ELECTROOPTICAL OR ELECTRONIC DEVICES LIKE FOR EXAMPLE ORGANIC FIELD EFFECT TRANSISTORS (FET OR OFET) FOR THIN FILM TRANSISTOR LIQUID CRYSTAL DISPLAYS AND INTEGRATED CIRCUIT MERCK PATENT GESELLESHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2004-10-05 — — US disclosed
US-20040175638-A1 Polymerisable charge transport compounds MERCK PATENT GESELLSCHAFT (DE) 2004-09-09 — — US disclosed
EP-1404683-A2 POLYMERISABLE CHARGE TRANSPORT COMPOUNDS MERCK PATENT GmbH (DE) 2004-04-07 — — EP disclosed
EP-1274713-B1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIV CARDIFF (GB) 2004-03-10 — — EP disclosed
US-20030148967-A1 Anti-viral pyrimidine nucleoside analogues REGA FOUNDATION (BE) 2003-08-07 — — US disclosed
US-20030080322-A1 Reactive thienothiophenes MERCK PATENT GMBH (DE) 2003-05-01 — — US disclosed
WO-2003006468-A2 POLYMERISABLE CHARGE TRANSPORT COMPOUNDS MERCK PATENT GMBH (DE) 2003-01-23 — — WO disclosed
EP-1274713-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES University College Cardiff Consultants Limited (GB) 2003-01-15 — — EP disclosed
EP-1275650-A2 Thienthiophenes with polymerisable group MERCK PATENT GmbH (DE) 2003-01-15 — — EP disclosed
WO-2001083501-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2001-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015147-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES NSUN2, PNP, TDO2 HSD17B10 2668/4885TSHR 1094/4885ESR1 3857/4885
US-20140011764-A1 Anti-Viral Pyrimidine Nucleoside Analogues NSUN2, HCN2, TK1 HSD17B10 2605/4885TSHR 993/4885ESR1 3512/4885
US-20030148967-A1 Anti-viral pyrimidine nucleoside analogues NUDT1, DNTT, RNMT HSD17B10 1144/4885TSHR 2213/4885ESR1 4366/4885
US-20040175638-A1 Polymerisable charge transport compounds SLCO4C1, SLCO1A2, GFPT1 HSD17B10 3857/4885TSHR 1024/4885ESR1 2536/4885
US-20030080322-A1 Reactive thienothiophenes TST, ICMT, GFPT1 HSD17B10 2738/4885TSHR 253/4885ESR1 1569/4885
US-20160244476-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES NSUN2, PNP, CCNO HSD17B10 2665/4885TSHR 1120/4885ESR1 3763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.