SCHEMBL6706161

SCHEMBL6706161

COc1ccc(/C(C#N)=N\O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.57
▸ ALDH1A1 P00352 3/20 0.57
▸ NPSR1 Q6W5P4 3/20 0.51
▸ MAPK1 P28482 2/20 0.51
▸ HSP90AA1 P07900 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ PKM P14618 1/20 0.51
▸ GFER P55789 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ KDM4E B2RXH2 3/20 0.47
▸ NQO2 P16083 1/20 0.46
▸ MAPT P10636 3/20 0.46
▸ HPGD P15428 2/20 0.46
▸ TSHR P16473 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ NFKB1 P19838 1/20 0.46
▸ APEX1 P27695 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ PMP22 Q01453 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10172227 1.00 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL6706162 1.00 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL12994619 0.85 NPSR1 (0.47) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL10233427 0.85 NPSR1 (0.47) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL23504933 0.83 NPSR1 (0.50) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL1344768 0.83 NPSR1 (0.50) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL12454187 0.83 NPSR1 (0.46) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL1344772 0.83 NPSR1 (0.50) SMN1; SMN2ALDH1A1NPSR1MAPK1HSP90AA1
SCHEMBL10859395 0.81 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1NPSR1MAPK1KDM4E
SCHEMBL10859399 0.81 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1NPSR1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770420-B2 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity CIBA SPECIALTY CHEMICALS CORPORATION 2004-08-03 — — US disclosed
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity DIETLIKER KURT (CH) 2004-01-22 — — US disclosed
EP-0925529-B1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SC HOLDING AG (CH) 2003-04-16 — — EP disclosed
EP-0780729-B1 Chemical-sensitization photoresist composition TOKYO OHKA KOGYO CO LTD (JP) 2002-07-10 — — EP disclosed
EP-0821274-B1 Chemical-sensitization resist composition TOKYO OHKA KOGYO CO LTD (JP) 2001-11-14 — — EP disclosed
US-6245930-B1 AN OXIMESULFONATE COMPOUND CAPABLE OF GIVING POSITIVELY OR NEGATIVELY PATTERNED RESIST LAYER OF EXCELLENT PATTERN RESOLUTION, CROSS SECTIOANL PROFILE, AND HIGH SENSITIVITY TOKYO OHKA KOGYO CO., LTD. (JP) 2001-06-12 — — US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 — — US disclosed
US-6063953-A Chemical-sensitization photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 2000-05-16 — — US disclosed
US-6022666-A Chemical-sensitization photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 2000-02-08 — — US disclosed
US-5976760-A Chemical-sensitization resist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1999-11-02 — — US disclosed
EP-0925529-A1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY Ciba SC Holding AG (CH) 1999-06-30 — — EP disclosed
US-5902713-A Chemical-sensitization photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1999-05-11 — — US disclosed
EP-0571330-B1 High-resolution photoresist with enhanced sensitivity for I-line exposure CIBA GEIGY AG (CH) 1999-04-07 — — EP disclosed
US-5759740-A High resolution i-line photoresist of high sensitivity CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-02 — — US disclosed
WO-1998010335-A1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-03-12 — — WO disclosed
EP-0821274-A1 Chemical-sensitization resist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1998-01-28 — — EP disclosed
EP-0780729-A1 Chemical-sensitization photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 1997-06-25 — — EP disclosed
US-5627011-A High resolution i-line photoresist of high sensitivity CIBA-GEIGY CORPORATION (US) 1997-05-06 — — US disclosed
EP-0571330-A1 High-resolution photoresist with enhanced sensitivity for I-line exposure CIBA-GEIGY AG (CH) 1993-11-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity SULT1E1, CCNT1, CCNE1 SMN1; SMN2 1833/4885ALDH1A1 1150/4885NPSR1 3906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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