SCHEMBL6706300

SCHEMBL6706300

c1ccc(CCCCN(CCCCc2ccccc2)CCCCc2ccccc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.66
SIGMAR1 Q99720 4/20 0.65
CHRM2 P08172 1/20 0.65
HTR1A P08908 1/20 0.65
ADRA2A P08913 1/20 0.65
CHRM1 P11229 1/20 0.65
DRD1 P21728 1/20 0.65
SLC6A2 P23975 1/20 0.65
SLC6A4 P31645 1/20 0.65
ADRA1A P35348 1/20 0.65
OPRM1 P35372 1/20 0.65
DRD3 P35462 1/20 0.65
SLC6A3 Q01959 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10662405 0.98 SIGMAR1 (0.69) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL11699577 0.98 SIGMAR1 (0.69) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL10817335 0.92 KCNH2 (0.75) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL8083399 0.89 KCNH2 (0.56) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL28032419 0.89 SIGMAR1 (0.63) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL25180616 0.88 KCNH2 (0.69) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL8086575 0.88 KCNH2 (0.59) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL8569852 0.88 KCNH2 (0.80) KCNH2SIGMAR1CHRM2HTR1AADRA2A
SCHEMBL11135856 0.88 KCNH2 (0.86) KCNH2SIGMAR1CHRM2HTR1AADRA2A
Hydrochloric Acid SCHEMBL7404810 0.88 KCNH2 (0.54) KCNH2SIGMAR1CHRM2HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975019-A1 RUTHENIUM CATALYZED HYDROAMINOMETHYLATION Evonik Degussa GmbH (DE) 2016-01-20 EP disclosed
US-20040052961-A1 Electroless copper plating of ferrous metal substrates CHEMETALL GMBH (DE) 2004-03-18 US disclosed
EP-0554679-A1 Process for the preparation of alpha-Chloro 2,4,6-trimethylacetophenone BASF Aktiengesellschaft (DE) 1993-08-11 EP disclosed
EP-0211271-B1 PROCESS FOR THE PREPARATION OF VERATRYL CYANIDE BASF Aktiengesellschaft (DE) 1988-10-12 EP disclosed
EP-0142797-B1 METHOD FOR THE PREPARATION OF ACETONITRILES SUBSTITUTED IN POSITION 2 BY AN AROMATIC OR HETEROCYCLIC SUBSTITUENT BASF Aktiengesellschaft (DE) 1988-07-13 EP disclosed
US-4661610-A Preparation of veratryl cyanide BASF AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
EP-0211271-A1 Process for the preparation of veratryl cyanide BASF Aktiengesellschaft (DE) 1987-02-25 EP disclosed
EP-0142797-A2 Method for the preparation of acetonitriles substituted in position 2 by an aromatic or heterocyclic substituent BASF Aktiengesellschaft (DE) 1985-05-29 EP disclosed
EP-0046194-B1 PROCESS FOR THE PREPARATION OF O,O-DISUBSTITUTED BENZOIC ACIDS AND THEIR SALTS BASF Aktiengesellschaft (DE) 1983-10-05 EP disclosed
EP-0019158-B1 PROCESS FOR THE PRODUCTION OF M-SUBSTITUTED N-METHYLANILINES BASF Aktiengesellschaft (DE) 1982-09-15 EP disclosed
EP-0046194-A1 Process for the preparation of o,o-disubstituted benzoic acids and their salts BASF Aktiengesellschaft (DE) 1982-02-24 EP disclosed
EP-0019158-A1 Process for the production of m-substituted N-methylanilines BASF Aktiengesellschaft (DE) 1980-11-26 EP disclosed