SCHEMBL670644

SCHEMBL670644

COC(=O)c1ccc(O)c(C(C)=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.67
CA2 P00918 7/20 0.67
CA12 O43570 6/20 0.67
CA7 P43166 6/20 0.67
CA9 Q16790 6/20 0.67
CA14 Q9ULX7 6/20 0.67
XDH P47989 2/20 0.67
KDM4E B2RXH2 4/20 0.59
ALDH1A1 P00352 4/20 0.59
HSD17B10 Q99714 4/20 0.59
LMNA P02545 3/20 0.59
HPGD P15428 3/20 0.59
MAPT P10636 2/20 0.59
HTT P42858 2/20 0.59
TP53 P04637 2/20 0.59
ALOX15 P16050 2/20 0.59
ALOX12 P18054 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29826125 1.00 CA1 (0.67) CA1CA2CA12CA7CA9
SCHEMBL403210 0.89 CA12 (0.71) CA1CA2CA12CA7CA9
SCHEMBL15660162 0.86 CA12 (0.62) CA1CA2CA12CA7CA9
SCHEMBL330670 0.85 CA12 (0.65) CA1CA2CA12CA7CA9
SCHEMBL136284 0.85 CA1 (0.67) CA1CA2CA12CA7CA9
SCHEMBL15543469 0.85 TDP1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL5917807 0.85 CA12 (0.67) CA1CA2CA12CA7CA9
SCHEMBL31258831 0.85 CA12 (0.65) CA1CA2CA12CA7CA9
SCHEMBL552572 0.84 CA12 (0.65) CA1CA2CA12CA7CA9
SCHEMBL2459449 0.83 KDM4E (0.62) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. 2025-05-22 US disclosed
CN-115427035-B ENL/AF9 YEATS inhibitors 洛克菲勒大学 2025-04-22 CN disclosed
CN-118638089-B Preparation method for synthesizing flavonoid compound based on carbon dioxide 湖南工程学院 2024-11-12 CN disclosed
CN-118638089-A Preparation method for synthesizing flavonoid compound based on carbon dioxide 湖南工程学院 2024-09-13 CN disclosed
US-20240166617-A1 PHOSPHOINOSITIDE 3 KINASE BETA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF GEODE THERAPEUTICS INC (US) 2024-05-23 US disclosed
US-20240158390-A1 OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV JANSSEN SCIENCES IRELAND UNLMITED COMPANY (IE) 2024-05-16 US disclosed
EP-4359381-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-05-01 EP disclosed
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 CN disclosed
CN-117615763-A Phosphoinositide 3 kinase beta inhibitor, composition and preparation method thereof 健道生物医药有限公司 2024-02-27 CN disclosed
EP-4284375-A1 PHOSPHOINOSITIDE 3 KINASE BETA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF Geode Therapeutics Inc. (US) 2023-12-06 EP disclosed
US-4183945-A ANTIANAPHYLACTIC AGENTS CARLO ERBA S.P.A. (IT) 1980-01-15 US disclosed
US-4177276-A ANIT-ALLERGY ACTIVITY FARMITALIA CARLO ERBA, S.P.A. (IT) 1979-12-04 US disclosed
US-4177286-A ANTIALLERGENS FARMITALIA CARLO ERBA, S.P.A. (IT) 1979-12-04 US disclosed
US-4157334-A ANTIALLERGENS, SPASMOLYTIC CARLO ERBA S. P. A. (IT) 1979-06-05 US disclosed
US-4152449-A ANTIALLERGENS CARLO ERBA S. P. A. (IT) 1979-05-01 US disclosed
US-4148900-A ANTIALLERGIC CARLO ERBA S.P.A. (IT) 1979-04-10 US disclosed
US-4143145-A ANTIALLERGENS CARLO ERBA S. P. A. (IT) 1979-03-06 US disclosed
US-4115567-A TREATMENT OF ALLERGIES CARLO ERBA S. P. A. (IT) 1978-09-19 US disclosed
US-4083953-A ANTIALLERGENS CARLO ERBA, S.P.A. (IT) 1978-04-11 US disclosed
US-4065467-A ANTIALLERGENS, ANTIULCER AGENTS, TREATMENT OF RESPIRATORY SYSTEM AND PULMONARY DISORDERS CARLO ERBA, S. P. A. (IT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC CA1 4855/4885CA2 4707/4885CA12 4823/4885
US-20240158390-A1 OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV MAVS, ZC3HAV1, RNASEH1 CA1 4820/4885CA2 3533/4885CA12 3925/4885
US-20240166617-A1 PHOSPHOINOSITIDE 3 KINASE BETA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF PIK3CA, PIK3CB, PI4KA CA1 2855/4885CA2 2216/4885CA12 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.