Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686791 | 0.92 | FGFR4 (0.39) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4686754 | 0.91 | EGFR (0.38) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL14290437 | 0.91 | EGFR (0.38) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4689937 | 0.91 | FGFR4 (0.40) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL6212461 | 0.90 | EGFR (0.38) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| Acetic Acid SCHEMBL4687570 | 0.90 | EGFR (0.37) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4690757 | 0.89 | FGFR4 (0.39) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| Acetic Acid SCHEMBL4686845 | 0.88 | FGFR4 (0.38) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4686694 | 0.85 | FGFR4 (0.39) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL4686744 | 0.85 | FGFR4 (0.45) | EGFRFGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038995-A1 | Pyrimido compounds having antiproliferative activity | CHEN YI (US) | 2004-02-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038995-A1 | Pyrimido compounds having antiproliferative activity | LCK, FGFR1, FGFR3 | EGFR 45/4885FGFR4 5/4885FGFR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.