Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710205 | 0.87 | KCNA5 (0.46) | KCNA5KCNH2CYP2D6KCNE1MEN1 | |
| SCHEMBL7449241 | 0.82 | KCNA5 (0.54) | KCNA5KCNH2CYP2D6KCNE1MEN1 | |
| SCHEMBL6708539 | 0.78 | ATM (0.33) | CYP2D6SMN1; SMN2CYP2C19KDM4ECYP2C9 | |
| SCHEMBL443975 | 0.75 | CYP3A4 (0.42) | KCNA5KCNH2CYP2D6KCNE1MEN1 | |
| SCHEMBL1432767 | 0.75 | AOC3 (0.39) | KCNH2CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1456060 | 0.74 | SLC6A3 (0.44) | KCNA5KCNH2CYP2D6KCNE1MEN1 | |
| SCHEMBL12488384 | 0.73 | KCNA5 (0.51) | KCNA5KCNH2CYP2D6KCNE1MEN1 | |
| SCHEMBL1807175 | 0.72 | KCNA5 (0.51) | KCNA5KCNH2CYP2D6KCNE1MEN1 | |
| SCHEMBL23969993 | 0.72 | KCNH2 (0.55) | KCNA5KCNH2CYP2D6KCNE1CYP1A2 | |
| SCHEMBL2957267 | 0.72 | TSHR (0.58) | KCNA5KCNH2CYP2D6KCNE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040019068-A1 | Novel remedies or preventives for angiostenosis | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019068-A1 | Novel remedies or preventives for angiostenosis | CMA1, ACE, AGTR1 | KCNA5 3211/4885KCNH2 2496/4885CYP2D6 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.