Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.69 |
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 5/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258969 | 0.99 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL9767559 | 0.99 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL7602089 | 0.92 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL6705598 | 0.86 | MAPT (0.58) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL11463673 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL11544615 | 0.85 | MAPT (0.73) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL385476 | 0.84 | KDM4E (0.79) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL385477 | 0.84 | KDM4E (0.79) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL29360251 | 0.84 | KDM4E (0.79) | SMN1; SMN2RAB9AKDM4EMAPTHPGD | |
| SCHEMBL11341691 | 0.84 | MAPT (0.85) | SMN1; SMN2RAB9AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040238791-A1 | Reinforcement of the effect of optical brighteners by means of polymers | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | US | disclosed |