Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | HPGD | P15428 | 8/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.71 |
| ▸ | RELA | Q04206 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 6/20 | 0.66 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258969 | 1.00 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL6707325 | 0.99 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL7602089 | 0.93 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL6705598 | 0.87 | MAPT (0.58) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL11463673 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL11544615 | 0.86 | MAPT (0.73) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL385476 | 0.85 | KDM4E (0.79) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL29360251 | 0.85 | KDM4E (0.79) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL385477 | 0.85 | KDM4E (0.79) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL11341691 | 0.85 | MAPT (0.85) | SMN1; SMN2RAB9AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030917-B2 | OPTICAL BRIGHTENERS FROM BISTYRYL BENZENE, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |
| US-5001253-A | Fluorescent brighteners consisting of bis-styrylbenzene compounds, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4785128-A | Process for the preparation of bis-styrylbenzenes | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| US-4778623-A | Fluorescent brighteners consisting of bis-styrylbenzene compounds, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0030917-B1 | OPTICAL BRIGHTENERS FROM BISTYRYL BENZENE, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0030917-A2 | Optical brighteners from bistyryl benzene, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-06-24 | — | — | EP | disclosed |