Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398932 | 0.87 | HTT (0.52) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL2777679 | 0.87 | HTT (0.52) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL1398933 | 0.87 | HTT (0.52) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL28086104 | 0.83 | ITGB3 (0.51) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL6705791 | 0.83 | MEN1 (0.44) | CTSSMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3584842 | 0.83 | CTSS (0.52) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL2963801 | 0.83 | CTSS (0.52) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL5970504 | 0.83 | CTSS (0.57) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL1150932 | 0.83 | CTSS (0.57) | CTSSMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL1150931 | 0.83 | CTSS (0.57) | CTSSMEN1KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040030155-A1 | Process for preparing active esters | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-02-12 | — | — | US | claimed |
| EP-1350790-A1 | PROCESS FOR PREPARING ACTIVE ESTERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-10-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030155-A1 | Process for preparing active esters | CES1, CYP3A4, CYP3A5 | CTSS 711/4885MEN1 1633/4885KMT2A 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.