Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708056 | 0.91 | HIF1A (0.46) | HIF1AMEN1KMT2AGRM5 | |
| SCHEMBL6710167 | 0.90 | ESR1 (0.38) | HIF1ACYP1A2 | |
| SCHEMBL6710001 | 0.89 | HIF1A (0.34) | HIF1A | |
| SCHEMBL6709888 | 0.88 | HIF1A (0.47) | HIF1A | |
| SCHEMBL6710321 | 0.87 | MAPT (0.42) | HIF1ACYP1A2CYP3A4MAPT | |
| SCHEMBL6708765 | 0.87 | HIF1A (0.43) | HIF1A | |
| SCHEMBL6711782 | 0.86 | HIF1A (0.41) | HIF1AMEN1KMT2AGRM5MAPT | |
| SCHEMBL6710147 | 0.85 | TP53 (0.34) | HIF1AMEN1KMT2ACYP1A2MAPT | |
| SCHEMBL6707842 | 0.85 | HIF1A (0.43) | HIF1AMEN1KMT2AGRM5MAPT | |
| SCHEMBL6711786 | 0.85 | TNIK (0.38) | HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885ABCC9 3310/4885TMPRSS4 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.