Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712077 | 0.91 | GRIK1 (0.39) | GRIK1ROCK1F10 | |
| SCHEMBL6707962 | 0.90 | GRIK1 (0.40) | GRIK1ROCK1MEN1KMT2A | |
| SCHEMBL6712131 | 0.89 | F10 (0.34) | ROCK1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6712244 | 0.88 | GRIK1 (0.38) | GRIK1ROCK1MEN1KMT2A | |
| SCHEMBL6711606 | 0.85 | GRIK1 (0.42) | GRIK1ROCK1MEN1NPC1RAB9A | |
| SCHEMBL6709841 | 0.85 | GRIK1 (0.40) | GRIK1ROCK1KMT2A | |
| SCHEMBL6710225 | 0.84 | GRIK1 (0.42) | GRIK1ROCK1MEN1NPC1RAB9A | |
| SCHEMBL6711796 | 0.84 | HIF1A (0.36) | ROCK1F10F2PRSS1PRSS2 | |
| SCHEMBL6708769 | 0.84 | GRIK1 (0.39) | GRIK1ROCK1NPC1KMT2A | |
| SCHEMBL6710300 | 0.84 | GRIK1 (0.38) | GRIK1ROCK1MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885ROCK1 4830/4885MEN1 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.