Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP12 | P39900 | 2/20 | 0.54 |
| ▸ | RARB | P10826 | 2/20 | 0.51 |
| ▸ | RARG | P13631 | 2/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937361 | 0.88 | MMP2 (0.69) | MMP2MMP12RARBRARGFFAR1 | |
| SCHEMBL30143434 | 0.86 | MMP2 (0.72) | MMP2MMP12RARBFFAR1FFAR4 | |
| SCHEMBL6934491 | 0.86 | MMP2 (0.72) | MMP2MMP12RARBFFAR1FFAR4 | |
| SCHEMBL4271492 | 0.86 | MMP2 (0.72) | MMP2MMP12RARBFFAR1FFAR4 | |
| SCHEMBL6240989 | 0.84 | MMP2 (0.49) | MMP2MMP12HAO1FFAR1FFAR4 | |
| SCHEMBL6936308 | 0.82 | MMP2 (0.67) | MMP2MMP12RARBFFAR1FFAR4 | |
| SCHEMBL17676105 | 0.81 | ALDH1A1 (0.53) | MMP2MMP12HAO1FFAR1FFAR4 | |
| SCHEMBL14168593 | 0.81 | HDAC1 (0.48) | MMP2MMP12 | |
| SCHEMBL1314738 | 0.80 | MMP2 (0.49) | MMP2MMP12RARBRARGHCAR2 | |
| SCHEMBL6708132 | 0.80 | CA1 (0.54) | MMP2MMP12ALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | MMP2 4401/4885MMP12 3889/4885RARB 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.