Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66607 | 0.88 | TAAR1 (0.61) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| Formaldehyde SCHEMBL28263667 | 0.85 | TAAR1 (0.57) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL18003547 | 0.80 | MAOB (0.50) | TAAR1MAOBHDAC1HDAC8ACP3 | |
| SCHEMBL1509 | 0.79 | TAAR1 (0.57) | TAAR1MAOBHDAC1HDAC8MEN1 | |
| SCHEMBL7870943 | 0.79 | TAAR1 (0.57) | TAAR1HDAC1HDAC8ACP3MAPT | |
| SCHEMBL9689196 | 0.79 | TAAR1 (0.50) | TAAR1MAOBHDAC1HDAC8MEN1 | |
| SCHEMBL9689194 | 0.79 | TAAR1 (0.50) | TAAR1MAOBHDAC1HDAC8MEN1 | |
| SCHEMBL19399695 | 0.78 | TAAR1 (0.56) | TAAR1HDAC1HDAC8ACP3MAPT | |
| Styrene SCHEMBL28262481 | 0.77 | TAAR1 (0.46) | TAAR1MAOBMEN1KMT2AKDM4E | |
| SCHEMBL21177003 | 0.77 | CYP1A2 (0.37) | TAAR1HDAC1HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044657-A1 | BIOCATALYSTS AND METHODS THEREOF | TESARO, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-2935572-A1 | ENGINEERED BIOCATALYSTS AND METHODS FOR SYNTHESIZING CHIRAL AMINES | Codexis, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2828385-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | Codexis, Inc. (US) | 2015-01-28 | — | — | EP | disclosed |
| WO-2014099730-A1 | ENGINEERED BIOCATALYSTS AND METHODS FOR SYNTHESIZING CHIRAL AMINES | CODEXIS, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013142770-A1 | BIOCATALYSTS AND METHODS FOR SYNTHESIZING DERIVATIVES OF TRYPTAMINE AND TRYPTAMINE ANALOGS | CODEXIS, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| EP-2606139-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | Codexis, Inc. (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024104-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (1R,2R)-2-(3,4-DIMETHOXYPHENETHOXY)CYCLOHEXANAMINE | CODEXIS, INC. (US) | 2012-02-23 | — | — | WO | disclosed |