Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399695 | 0.95 | TAAR1 (0.56) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL66607 | 0.90 | TAAR1 (0.61) | TAAR1HDAC1HDAC8MIFACP3 | |
| Formaldehyde SCHEMBL28263667 | 0.87 | TAAR1 (0.57) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL11516989 | 0.83 | TAAR1 (0.57) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL5535930 | 0.83 | TAAR1 (0.53) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL5540234 | 0.81 | HDAC1 (0.54) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL1045499 | 0.81 | TAAR1 (0.62) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL18003547 | 0.81 | MAOB (0.50) | TAAR1HDAC1HDAC8MIFACP3 | |
| SCHEMBL39835 | 0.80 | TAAR1 (0.56) | TAAR1MIFACP3DAOIDO1 | |
| SCHEMBL2095502 | 0.80 | TAAR1 (0.53) | TAAR1HDAC1HDAC8MIFACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096070-B | Method for producing m-trifluoromethyl phenylpropyl aldehyde | 中国石油化工股份有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-109180496-B | Method for synthesizing cinacalcet by using chemical-enzymatic method | 浙江大学 | 2021-02-09 | — | — | CN | disclosed |
| EP-2406211-B1 | A NEW METHOD FOR THE PREPARATION OF CINACALCET AND NEW INTERMEDIATES THEREOF | MEGAFINE PHARMA P LTD (IN) | 2018-06-27 | — | — | EP | disclosed |
| US-8969623-B2 | Method for the preparation of cinacalcet and intermediates and impurities thereof | Amneal Pharmaceuticals, LLC (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140081048-A1 | Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof | MEGAFINE PHARMA (P) LTD. (IN) | 2014-03-20 | — | — | US | disclosed |
| US-8575395-B2 | Method for the preparation of cinacalcet and intermediates and impurities thereof | Amneal Pharmaceuticals, LLC (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110319663-A1 | Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof | Amneal Pharmaceuticals, LLC (US) | 2011-12-29 | — | — | US | disclosed |
| WO-2010103531-A2 | A NEW METHOD FOR THE PREPARATION OF CINACALCET AND NEW INTERMEDIATES THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2010-09-16 | — | — | WO | disclosed |
| EP-0194764-B1 | PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-07-12 | — | — | EP | disclosed |
| EP-0194764-A1 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319663-A1 | Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof | CMA1, SI, ALDH1A1 | TAAR1 1331/4885HDAC1 1038/4885HDAC8 3514/4885 |
| US-20140081048-A1 | Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof | CMA1, SI, ALDH1A1 | TAAR1 1331/4885HDAC1 1038/4885HDAC8 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.