Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387580 | 1.00 | CHRM5 (0.37) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL670851 | 1.00 | CHRM5 (0.37) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL2079988 | 0.83 | CREBBP (0.36) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL3436250 | 0.83 | CREBBP (0.36) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL12984738 | 0.75 | HCAR2 (0.41) | SMN1; SMN2KMT2A | |
| SCHEMBL671480 | 0.74 | TBXA2R (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL671481 | 0.74 | TBXA2R (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL475667 | 0.74 | CHRM2 (0.44) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL955271 | 0.74 | CHRM2 (0.44) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL475670 | 0.74 | CHRM2 (0.44) | CHRM5CHRM3CHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-9085567-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140249192-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2014-09-04 | — | — | US | disclosed |
| EP-2606044-B1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN INC (US) | 2014-06-04 | — | — | EP | disclosed |
| CN-103619837-A | Fatty acid amide hydrolase inhibitors for treating pain | ALLERGAN INC | 2014-03-05 | — | — | CN | disclosed |
| EP-2699565-A1 | FATTY ACID AMIDE HYDROLASE INHIBITORS FOR TREATING PAIN | Allergan, Inc. (US) | 2014-02-26 | — | — | EP | disclosed |
| US-8653118-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| EP-2606044-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2013-06-26 | — | — | EP | disclosed |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| CN-103119039-A | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN INC | 2013-05-22 | — | — | CN | disclosed |
| WO-2012145737-A1 | FATTY ACID AMIDE HYDROLASE INHIBITORS FOR TREATING | ALLERGAN, INC. (US) | 2012-10-26 | — | — | WO | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2012024559-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | CHRM5 728/4885CHRM3 312/4885CHRM2 638/4885 |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | FAAH, FAAH2, FAH | CHRM5 4222/4885CHRM3 3507/4885CHRM2 3875/4885 |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | CHRM5 616/4885CHRM3 289/4885CHRM2 588/4885 |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | CHRM5 728/4885CHRM3 312/4885CHRM2 638/4885 |
| US-20140249192-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | CHRM5 728/4885CHRM3 312/4885CHRM2 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.