Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.38 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713158 | 0.93 | MAPT (0.39) | MAPTMAPK1TDP1PTK2BMAP3K5 | |
| SCHEMBL6710068 | 0.90 | MAPT (0.41) | MAPTMAPK1TDP1PTK2BMAP3K5 | |
| SCHEMBL6709889 | 0.89 | MAPT (0.43) | MAPTMAPK1TDP1ALDH1A1LMNA | |
| SCHEMBL6710087 | 0.88 | PLCG2 (0.39) | MAPTMAPK1TDP1KDM4EALDH1A1 | |
| SCHEMBL6709837 | 0.88 | MAPT (0.39) | MAPTMAPK1TDP1PTK2BMAP3K5 | |
| SCHEMBL6712028 | 0.88 | MAP3K5 (0.38) | MAPTMAPK1TDP1ALDH1A1RAB9A | |
| SCHEMBL6710112 | 0.87 | MAP3K5 (0.45) | MAPTMAPK1TDP1KDM4ERAB9A | |
| SCHEMBL6710315 | 0.87 | POLB (0.39) | MAPTMAPK1TDP1ALDH1A1PTK2B | |
| SCHEMBL6713754 | 0.85 | SERPINE1 (0.43) | KDM4EPLCG2NHERF1NSD2 | |
| SCHEMBL6707884 | 0.85 | HDAC3 (0.40) | MAPTMAPK1TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | MAPT 4754/4885MAPK1 2728/4885TDP1 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.