Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13923335 | 0.92 | KDM4E (0.80) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8038539 | 0.91 | KDM4E (0.79) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29475791 | 0.91 | KDM4E (0.79) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL27672529 | 0.90 | KDM4E (0.76) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL6742652 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL17554684 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL149150 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL29349852 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL8027963 | 0.88 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Enrofloxacin SCHEMBL976909 | 0.88 | KDM4E (0.98) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | NATCO PHARMA LIMITED (IN) | 2004-04-15 | — | — | US | disclosed |
| EP-1282603-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF QUINOLONE DERIVATIVES | Natco Pharma Limited (IN) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001085692-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF QUINOLONE DERIVATIVES | NATCO PHARMA LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | CBR1, CYP4X1, NRAS | KDM4E 3682/4885ALDH1A1 1601/4885LMNA 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.