Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711789 | 0.90 | PARP14 (0.36) | PKMTP53MAPTPOLBPARP14 | |
| SCHEMBL6712259 | 0.90 | GAA (0.38) | PKMTP53MAPTPOLBPARP14 | |
| SCHEMBL6711757 | 0.90 | NR1H4 (0.35) | PKMTP53MAPTPOLBRXFP1 | |
| SCHEMBL6708969 | 0.90 | MAP3K5 (0.37) | PKMTP53MAPTPOLBPARP14 | |
| SCHEMBL6711927 | 0.90 | PARP14 (0.44) | TP53MAPTPOLBPARP14LMNA | |
| SCHEMBL6713375 | 0.89 | PARP14 (0.39) | PKMTP53MAPTPOLBRXFP1 | |
| SCHEMBL6710250 | 0.89 | KMT2A (0.42) | TP53RXFP1PARP14HDAC1NSD2 | |
| SCHEMBL6710380 | 0.89 | MAP3K5 (0.43) | PKMTP53MAPTPOLBRXFP1 | |
| SCHEMBL6709996 | 0.89 | GSK3B (0.42) | TP53MAPTPOLBRXFP1PARP14 | |
| SCHEMBL6713522 | 0.88 | PARP14 (0.41) | PKMTP53MAPTPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PKM 3958/4885TP53 2699/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.