Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 4/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711762 | 0.89 | MAP3K5 (0.41) | PLA2G7NSD2NR1H4TP53POLB | |
| SCHEMBL6710449 | 0.88 | KMT2A (0.43) | POLBLMNA | |
| SCHEMBL6710492 | 0.88 | GRIK1 (0.41) | RARAPLA2G7NSD2TP53POLB | |
| SCHEMBL6711696 | 0.88 | GRIK1 (0.39) | RARANSD2TP53POLBMAP3K5 | |
| SCHEMBL6707720 | 0.87 | MEN1 (0.36) | PLA2G7TP53LMNA | |
| SCHEMBL6708854 | 0.87 | KMT2A (0.42) | PLA2G7NSD2NR1H4MAPTPKM | |
| SCHEMBL6709008 | 0.86 | MAPT (0.36) | PLA2G7NSD2TP53POLBMAP3K5 | |
| SCHEMBL6713406 | 0.86 | NPC1 (0.41) | PLA2G7LMNA | |
| SCHEMBL6710055 | 0.86 | IRAK4 (0.41) | PLA2G7NR1H4GRM5PKM | |
| SCHEMBL6713424 | 0.86 | GSK3B (0.40) | PLA2G7NSD2TP53MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | RARA 182/4885PLA2G7 3314/4885NSD2 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.