Styrene

Styrene

SCHEMBL6709068

C=C(CCC)C(=O)OCCCCCC.C=Cc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
LMNA P02545 4/20 0.47
ALDH1A1 P00352 3/20 0.47
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
KDM4E B2RXH2 3/20 0.42
POLB P06746 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PPARG P37231 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL5873264 0.93 LMNA (0.41) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL491216 0.91 TSHR (0.48) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL18789030 0.90 KDM4E (0.46) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL10533310 0.88 TSHR (0.45) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL9754626 0.87 KDM4E (0.43) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL1984291 0.87 TSHR (0.65) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL6762849 0.87 TSHR (0.65) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL1978653 0.87 TSHR (0.65) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL4205045 0.87 TSHR (0.65) TSHRLMNAALDH1A1TP53CYP3A4
Styrene SCHEMBL9718413 0.86 HCAR2 (0.48) TSHRLMNAALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040170912-A1 formulation of nonmagnetic toners for use in a non-magnetic toning system (NMTS) comprising:a primary toner resin, a propylene wax, a charge control additive, and a primary colorant LOGICAL IMAGING SOLUTIONS, INC. 2004-09-02 US claimed
US-5834150-A DRY TONER; PRIMARY RESIN SOLUBLE IN A HYDROCHLOROFLUOROCARBON, AN INSOLUBLE SECONDARY RESIN, AND A COLORANT INTERSCIENCE COMPUTER CORPORATION (US) 1998-11-10 US claimed
WO-1997007432-A1 SOLVENT VAPOR FIXING METHODS AND PROCESS COLOR TONERS FOR USE IN SAME INTERSCIENCE COMPUTER CORPORATION (US) 1997-02-27 WO claimed
US-20040170912-A1 formulation of nonmagnetic toners for use in a non-magnetic toning system (NMTS) comprising:a primary toner resin, a propylene wax, a charge control additive, and a primary colorant LOGICAL IMAGING SOLUTIONS, INC. 2004-09-02 US disclosed
US-5834150-A DRY TONER; PRIMARY RESIN SOLUBLE IN A HYDROCHLOROFLUOROCARBON, AN INSOLUBLE SECONDARY RESIN, AND A COLORANT INTERSCIENCE COMPUTER CORPORATION (US) 1998-11-10 US disclosed
EP-0566835-B1 Electrophotographic toner HODOGAYA CHEMICAL CO LTD (JP) 1997-05-14 EP disclosed
EP-0566835-A1 Electrophotographic toner HODOGAYA CHEMICAL CO., LTD. (JP) 1993-10-27 EP disclosed