Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869895 | 0.94 | ACHE (0.46) | ACHEBCHE | |
| SCHEMBL6709135 | 0.92 | ACHE (0.38) | ACHEBCHEUTS2R | |
| SCHEMBL3863040 | 0.89 | ACHE (0.51) | ACHEBCHEUTS2R | |
| Hydrochloric Acid SCHEMBL3864932 | 0.88 | ACHE (0.50) | ACHEBCHE | |
| SCHEMBL3868386 | 0.84 | NPC1 (0.40) | ACHEBCHEUTS2R | |
| SCHEMBL3869062 | 0.82 | ACHE (0.55) | ACHEBCHE | |
| SCHEMBL3874406 | 0.81 | L3MBTL1 (0.42) | UTS2R | |
| Hydrochloric Acid SCHEMBL3867362 | 0.81 | ACHE (0.54) | ACHEBCHE | |
| SCHEMBL3868374 | 0.80 | ACHE (0.44) | ACHEBCHE | |
| SCHEMBL3866063 | 0.80 | ACHE (0.52) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067981-A1 | Acetylcholinesterase inhibitor; Alzheimer's diseases, Hubtington disease, antidepressants | SANKYO COMPANY, LIMITED (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067981-A1 | Acetylcholinesterase inhibitor; Alzheimer's diseases, Hubtington disease, antidepressants | ACHE, BACE1, CHRNA6 | ACHE 1/4885BCHE 51/4885UTS2R 4653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.