Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709509 | 0.84 | ATM (0.47) | ATMLSSL3MBTL1F10KLK1 | |
| SCHEMBL6737720 | 0.82 | F10 (0.42) | ATMPARP1DHODHF10KLK1 | |
| SCHEMBL6421218 | 0.82 | F10 (0.51) | ATMLSSL3MBTL1F10KLK1 | |
| SCHEMBL6421211 | 0.82 | F10 (0.51) | ATMLSSL3MBTL1F10KLK1 | |
| SCHEMBL6738660 | 0.79 | F10 (0.49) | ATMLSSL3MBTL1F10KLK1 | |
| SCHEMBL6729281 | 0.77 | ATM (0.57) | ATML3MBTL1F10KLK1LMNA | |
| SCHEMBL6421733 | 0.74 | F10 (0.71) | ATMLSSL3MBTL1F10KLK1 | |
| SCHEMBL5196283 | 0.74 | F10 (0.71) | LSSF10KLK1 | |
| SCHEMBL6547151 | 0.72 | ATM (0.52) | ATMLSSL3MBTL1F10KLK1 | |
| SCHEMBL6734496 | 0.72 | ALDH1A1 (0.44) | ATMLSSL3MBTL1F10KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753331-B1 | INDOL-2-YLSULPHONYL-4-(4-(HETEROCYCLE)BENZOYL)PIPERAZINE DERIVATIVES AS ANTICOAGULANTS | ASTRAZENECA AB (SE) | 2004-06-22 | — | — | US | disclosed |