Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036727 | 0.83 | AAK1 (0.41) | S1PR4XDH | |
| SCHEMBL12037052 | 0.83 | S1PR4 (0.53) | S1PR4 | |
| SCHEMBL28555443 | 0.81 | S1PR4 (0.41) | S1PR4BACE1XDH | |
| SCHEMBL16741129 | 0.81 | KMT2A (0.33) | BACE1XDH | |
| SCHEMBL8756155 | 0.81 | S1PR4 (0.40) | S1PR4XDH | |
| SCHEMBL23904774 | 0.81 | S1PR4 (0.35) | S1PR4XDH | |
| SCHEMBL16237931 | 0.81 | S1PR4 (0.35) | S1PR4BACE1XDH | |
| SCHEMBL8761798 | 0.79 | AAK1 (0.32) | — | |
| SCHEMBL28511868 | 0.77 | NQO2 (0.40) | — | |
| SCHEMBL8758820 | 0.76 | SYK (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248913-A1 | (Pyridinyl and pyrimidyl) trienoic acid derivatives as retinoid x receptor modulators | LIGAND PHARMACEUTICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1414450-A1 | (PYRIDINYL AND PYRIMIDYL)TRIENOIC ACID DERIVATIVES AS RETINOID X RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003007950-A1 | (PYRIDINYL AND PYRIMIDYL) TRIENOIC ACID DERIVATIVES AS RETINOID X RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248913-A1 | (Pyridinyl and pyrimidyl) trienoic acid derivatives as retinoid x receptor modulators | TSHR, THRA, RXRA | S1PR4 415/4885BACE1 4385/4885XDH 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.