Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808832 | 1.00 | ALOX5 (0.39) | ALOX5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL1079558 | 0.82 | ALOX5 (0.40) | ALOX5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL5481200 | 0.80 | ALOX5 (0.42) | ALOX5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL3925265 | 0.80 | ALOX5 (0.39) | ALOX5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL28706273 | 0.78 | TP53 (0.40) | ALOX5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL175346 | 0.78 | GLA (0.40) | ALOX5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL20213737 | 0.78 | KMT2A (0.38) | ALOX5NPC1RAB9AKMT2ACES2 | |
| SCHEMBL24767490 | 0.77 | SLC6A2 (0.49) | KMT2ASLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL14878718 | 0.77 | CACNA2D1 (0.43) | ALOX5LMNATP53POLBTHRB | |
| SCHEMBL6002738 | 0.77 | ALOX5 (0.37) | ALOX5NPC1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109551-A4 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECH INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1109551-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | Competitive Technologies, Inc. (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000010564-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECHNOLOGIES, INC. (US) | 2000-03-02 | — | — | WO | disclosed |