SCHEMBL175346

SCHEMBL175346

CCCCC(C)c1cccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CTSK P43235 2/20 0.38
ALOX5 P09917 1/20 0.38
HDAC3 O15379 1/20 0.35
LMNA P02545 2/20 0.35
RECQL P46063 1/20 0.35
MAPT P10636 1/20 0.35
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
THRB P10828 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22025440 0.94 ALOX5 (0.37) GLATSHRHTTL3MBTL1CTSK
SCHEMBL4948031 0.93 HDAC1 (0.38) GLATSHRHTTL3MBTL1CTSK
SCHEMBL1079558 0.88 ALOX5 (0.40) TSHRALOX5LMNAMAPTTP53
SCHEMBL28706273 0.85 TP53 (0.40) ALOX5LMNAMAPTTP53POLB
SCHEMBL6002738 0.83 ALOX5 (0.37) ALOX5LMNATP53POLBTHRB
SCHEMBL29211205 0.81 CTSK (0.39) GLATSHRHTTL3MBTL1CTSK
SCHEMBL7284168 0.81 NPC1 (0.50) GLATSHRHTTL3MBTL1CTSK
SCHEMBL7269210 0.81 NPC1 (0.50) GLATSHRHTTL3MBTL1CTSK
SCHEMBL7276887 0.81 NPC1 (0.50) GLATSHRHTTL3MBTL1CTSK
SCHEMBL12311962 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
CN-105473002-A 1H-PYRROLE-2,4-DICARBONYL-DERIVATIVES AND THEIR USE AS FLAVORING AGENTS FRESENIUS KABI DE GMBH 2016-04-06 CN claimed
CN-103503201-A High energy density redox flow device 24M TECHNOLOGIES INC 2014-01-08 CN claimed
CN-117214240-B Multi-level structure miniature gas sensor and preparation method thereof 浙江大学嘉兴研究院 2024-12-13 CN disclosed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US disclosed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP disclosed
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP disclosed
CN-117214240-A Multi-level structure miniature gas sensor and preparation method thereof 浙江大学嘉兴研究院 2023-12-12 CN disclosed
CN-111408412-B Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization 中国石油化工股份有限公司 2023-05-09 CN disclosed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO disclosed
EP-0357571-B1 Pyrimidine nucleosides MEDIVIR AB (SE) 1996-04-03 EP disclosed
EP-0691333-A2 Pyrimidine derivatives, process for their preparation and their use as precursors Medivir Aktiebolag (SE) 1996-01-10 EP disclosed
US-5440040-A Drug for Aids therapy; viricides MEDIVIR AB (SE) 1995-08-08 US disclosed
US-5413735-A Displays and visual aids CANON KABUSHIKI KAISHA (JP) 1995-05-09 US disclosed
EP-0458347-A2 Liquid crystal composition and display device using same CANON KABUSHIKI KAISHA (JP) 1991-11-27 EP disclosed
EP-0357571-A2 Pyrimidine nucleosides Medivir Aktiebolag (SE) 1990-03-07 EP disclosed
WO-1989012061-A1 PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES MEDIVIR AB (SE) 1989-12-14 WO disclosed