Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL2944767 | 0.83 | TSHR (0.44) | CA1CA2NFKB1CYP3A4TSHR | |
| L-Lactic Acid SCHEMBL27740901 | 0.81 | CA1 (0.58) | CA1CA2NFKB1CES2CES1 | |
| Isopropyl Alcohol SCHEMBL5606351 | 0.78 | TSHR (0.42) | CA1TSHRCES2CES1 | |
| L-Lactic Acid SCHEMBL6072253 | 0.77 | CA1 (0.48) | CA1CA2NFKB1CYP3A4TSHR | |
| L-Lactic Acid SCHEMBL668437 | 0.77 | CA1 (0.54) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL1230198 | 0.77 | CA1 (0.44) | CA1CA2NFKB1CYP3A4TSHR | |
| SCHEMBL2952504 | 0.77 | CA1 (0.44) | CA1CA2NFKB1CYP3A4TSHR | |
| Tetrabuthylammonium SCHEMBL331981 | 0.76 | SLC22A1 (0.52) | CA1CA2NFKB1CYP3A4TSHR | |
| Valeric Acid SCHEMBL4734164 | 0.76 | CA1 (0.67) | CA1CA2NFKB1CES2CES1 | |
| L-Lactic Acid SCHEMBL3441408 | 0.76 | CA1 (0.47) | CA1CA2NFKB1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866101-B1 | PHOTOCATALYTIC COATING COMPOSITION AND PHOTOCATALYST-BEARING STRUCTURE | NIPPON SODA CO (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6407033-B1 | MIXTURE OF ZIRCONIUM AND TIN COMPOUND; ALKALI RESISTANCE | NIPPON SODA CO., LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-0866101-A1 | PHOTOCATALYTIC COATING COMPOSITION AND PHOTOCATALYST-BEARING STRUCTURE | NIPPON SODA CO., LTD. (JP) | 1998-09-23 | — | — | EP | disclosed |