Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009289 | 0.80 | HDAC4 (0.48) | ERN1ALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8736391 | 0.80 | CHRNB2 (0.48) | ERN1CYP11B1CYP11B2 | |
| SCHEMBL1802008 | 0.79 | ERN1 (0.59) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL16238334 | 0.78 | ERN1 (0.54) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL30252276 | 0.77 | ERN1 (0.57) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL14840485 | 0.77 | ERN1 (0.57) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL894805 | 0.77 | ERN1 (0.57) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL7101000 | 0.75 | ERN1 (0.54) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL6710790 | 0.74 | ERN1 (0.54) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL14919262 | 0.74 | ERN1 (0.57) | ERN1CYP3A4CYP2A6ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109551-A4 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECH INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1109551-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | Competitive Technologies, Inc. (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000010564-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECHNOLOGIES, INC. (US) | 2000-03-02 | — | — | WO | disclosed |