Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712425 | 0.93 | TP53 (0.38) | GRIK1LMNAMAPTGRM5PDE5A | |
| SCHEMBL6710044 | 0.92 | GRIK1 (0.36) | GRIK1LMNAMAPTBACE1GRM5 | |
| SCHEMBL6710289 | 0.91 | GRIK1 (0.36) | GRIK1LMNAMAPTBACE1GRM5 | |
| SCHEMBL6711990 | 0.91 | GRIK1 (0.40) | GRIK1LMNAMAPTBRPF1AKT1 | |
| SCHEMBL6709898 | 0.89 | GRIK1 (0.36) | GRIK1LMNAMAPTBRPF1BACE1 | |
| SCHEMBL6708956 | 0.89 | LRRK2 (0.38) | GRIK1LMNAMAPTBACE1 | |
| SCHEMBL6713672 | 0.89 | GRIK1 (0.36) | GRIK1LMNAMAPTBACE1GRM5 | |
| SCHEMBL6708800 | 0.89 | KDM1A (0.34) | LMNAMAPTBRPF1AKT1RXFP1 | |
| SCHEMBL6711788 | 0.89 | KDM1A (0.36) | GRIK1LMNAMAPTBACE1GRM5 | |
| SCHEMBL6710035 | 0.88 | GRIK1 (0.36) | GRIK1LMNAMAPTBACE1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885LMNA 4062/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.