Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 4/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710203 | 0.93 | PARP14 (0.41) | PARP14PTK2BRORCPTK2MAP3K5 | |
| SCHEMBL6711927 | 0.93 | PARP14 (0.44) | PARP14RORCMAPTLMNA | |
| SCHEMBL6713374 | 0.93 | NR1H4 (0.40) | PARP14PTK2BRORC | |
| SCHEMBL6712091 | 0.92 | PARP14 (0.39) | PARP14RORCMAPTMAP3K5LMNA | |
| SCHEMBL6713375 | 0.92 | PARP14 (0.39) | PARP14MAPTLMNABRD4HDAC1 | |
| SCHEMBL6765701 | 0.92 | CACNA1H (0.38) | PARP14RORCMAPTMAPK1MAP3K5 | |
| SCHEMBL6707721 | 0.92 | PARP14 (0.41) | PARP14SMN1; SMN2BRD4HDAC1 | |
| SCHEMBL6713731 | 0.92 | PARP14 (0.41) | PARP14RORCLMNA | |
| SCHEMBL6713494 | 0.91 | POLB (0.39) | PARP14MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL6711821 | 0.91 | PARP14 (0.38) | PARP14RORCMAPTBRD4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885PTK2B 4069/4885RORC 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.