Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709877 | 0.91 | GRIK1 (0.43) | GRIK1PLCG2MAPTMAPK1TDP1 | |
| SCHEMBL6707917 | 0.91 | GRIK1 (0.38) | GRIK1PLCG2MAPTMAPK1TDP1 | |
| SCHEMBL6710057 | 0.90 | GRIK1 (0.39) | GRIK1MAPTMAPK1TDP1TP53 | |
| SCHEMBL6712433 | 0.89 | GRIK1 (0.42) | GRIK1PLCG2MAPTMAPK1TDP1 | |
| SCHEMBL6712543 | 0.89 | GRIK1 (0.43) | GRIK1PLCG2MAPTTP53RXFP1 | |
| SCHEMBL6713948 | 0.89 | GRIK1 (0.41) | GRIK1PLCG2MAPTMAPK1TP53 | |
| SCHEMBL6711365 | 0.89 | GRIK1 (0.41) | GRIK1PLCG2MAPTTP53PLA2G7 | |
| SCHEMBL6713838 | 0.89 | GRIK1 (0.41) | GRIK1PLCG2MAPTTP53PLA2G7 | |
| SCHEMBL6712528 | 0.88 | GRIK1 (0.39) | GRIK1PLCG2MAPTMAPK1TDP1 | |
| SCHEMBL6709173 | 0.88 | GRIK1 (0.44) | GRIK1PLCG2MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885PLCG2 4289/4885CASP3 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.