Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710018 | 0.90 | DHODH (0.39) | HIF1AGRIK1ROCK1DHODHF2 | |
| SCHEMBL6713292 | 0.90 | HIF1A (0.47) | HIF1AGRIK1ROCK1F11KLKB1 | |
| SCHEMBL6711801 | 0.89 | HIF1A (0.43) | HIF1AGRIK1ROCK1F11KLKB1 | |
| SCHEMBL6708875 | 0.88 | DHODH (0.37) | HIF1AROCK1DHODHTHRBF2 | |
| SCHEMBL6709177 | 0.86 | HIF1A (0.42) | HIF1AROCK1SMURF1THRBF2 | |
| SCHEMBL6713252 | 0.86 | HIF1A (0.61) | HIF1AGRIK1ROCK1 | |
| SCHEMBL6708495 | 0.83 | HIF1A (0.45) | HIF1AGRIK1ROCK1F11KLKB1 | |
| SCHEMBL6708659 | 0.83 | GRIK1 (0.51) | HIF1AGRIK1ROCK1F11KLKB1 | |
| SCHEMBL6708990 | 0.83 | HIF1A (0.51) | HIF1AGRIK1ROCK1KCNMA1 | |
| SCHEMBL6709153 | 0.83 | EPHX2 (0.43) | HIF1AGRIK1ROCK1F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885GRIK1 3885/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.