Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707723 | 0.87 | GRIK1 (0.39) | HIF1ATP53POLBMAPT | |
| SCHEMBL6711761 | 0.87 | HIF1A (0.34) | HIF1ATP53POLBMAPT | |
| SCHEMBL6714364 | 0.87 | HIF1A (0.45) | HIF1APOLBMAPTHSP90AA1HSP90AB1 | |
| SCHEMBL6709879 | 0.87 | HIF1A (0.48) | HIF1ACSF1RF11KLKB1HSP90AA1 | |
| SCHEMBL6710040 | 0.87 | CSF1R (0.38) | HIF1ATP53POLBMAPTCSF1R | |
| SCHEMBL6707777 | 0.86 | HIF1A (0.38) | HIF1ALRRK2TP53POLBMAPT | |
| SCHEMBL6714271 | 0.86 | HIF1A (0.48) | HIF1A | |
| SCHEMBL6711746 | 0.85 | HIF1A (0.41) | HIF1ALRRK2TP53POLBMAPT | |
| SCHEMBL6713809 | 0.84 | HIF1A (0.43) | HIF1A | |
| SCHEMBL6708048 | 0.84 | TNIK (0.36) | HIF1ALRRK2TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885LRRK2 4612/4885KIT 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.