Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709177 | 0.90 | HIF1A (0.42) | F10F2HDAC6HIF1AROCK1 | |
| SCHEMBL6713659 | 0.90 | HIF1A (0.45) | GPR35HIF1AMEN1KMT2AROCK1 | |
| SCHEMBL6711582 | 0.90 | KMT2A (0.36) | GPR35F10F2HIF1AMEN1 | |
| SCHEMBL6710362 | 0.88 | F10 (0.36) | F10F2HDAC6HIF1AROCK1 | |
| SCHEMBL6710349 | 0.88 | HIF1A (0.38) | GPR35HIF1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6708059 | 0.86 | HIF1A (0.49) | HIF1AROCK1 | |
| SCHEMBL6710018 | 0.86 | DHODH (0.39) | GPR35F10F2HDAC6HIF1A | |
| SCHEMBL6707747 | 0.83 | HIF1A (0.35) | GPR35HIF1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6709169 | 0.83 | EPHX2 (0.41) | GPR35F10HIF1AMEN1KMT2A | |
| SCHEMBL6710038 | 0.83 | HIF1A (0.45) | GPR35HIF1AMEN1KMT2AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GPR35 2928/4885F10 2246/4885F2 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.