Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685257 | 0.87 | TSHR (0.46) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL5843057 | 0.79 | MAPT (0.47) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL27774101 | 0.76 | ALDH1A1 (0.59) | TSHRALDH1A1GLAMAPTKMT2A | |
| SCHEMBL128447 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL6152609 | 0.73 | ALDH1A1 (0.54) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL2197231 | 0.73 | ALDH1A1 (0.54) | TSHRALDH1A1GLAMAPTCRHBP | |
| Benzophenone SCHEMBL9593853 | 0.73 | ALDH1A1 (0.56) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL9437404 | 0.72 | ALDH1A1 (0.47) | TSHRALDH1A1GLAMAPTKMT2A | |
| SCHEMBL693898 | 0.72 | CHKA (0.42) | ALDH1A1NPSR1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5842489 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242867-A1 | Photoactivable nitrogen bases | CIBA CORPORATION | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242867-A1 | Photoactivable nitrogen bases | CBR3, NR2E3, RCOR3 | TSHR 321/4885ALDH1A1 2780/4885GLA 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.