Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528236 | 0.98 | MTNR1A (0.42) | MTNR1ANQO2FFAR4CASP1NPC1 | |
| SCHEMBL586305 | 0.86 | CYP1A2 (0.52) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL4514641 | 0.86 | ADRB2 (0.46) | MTNR1ANQO2FFAR4CASP1NPC1 | |
| SCHEMBL6538980 | 0.85 | NPC1 (0.49) | NPC1RAB9ATDP1CYP1A2CYP2C19 | |
| SCHEMBL143458 | 0.83 | MTNR1A (0.49) | MTNR1ANQO2NPC1RAB9ATDP1 | |
| SCHEMBL143128 | 0.80 | MTNR1A (0.47) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL11052717 | 0.78 | CYP1A2 (0.46) | MTNR1ANQO2TDP1KDM4ECYP1A2 | |
| SCHEMBL3113301 | 0.78 | CYP1A2 (0.44) | MTNR1ANQO2FFAR4TDP1CYP1A2 | |
| SCHEMBL4521520 | 0.78 | MTNR1A (0.45) | MTNR1ANQO2FFAR4TDP1KDM4E | |
| SCHEMBL3225216 | 0.78 | MTNR1A (0.45) | MTNR1ANQO2TDP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |