Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336922 | 0.89 | MAOA (0.41) | MAOAMAOB | |
| SCHEMBL6336924 | 0.89 | MAOA (0.41) | MAOAMAOB | |
| SCHEMBL6336919 | 0.89 | MAOA (0.41) | MAOAMAOB | |
| SCHEMBL6422776 | 0.89 | MAOA (0.41) | MAOAMAOB | |
| SCHEMBL6711455 | 0.84 | CALML3 (0.35) | MAOAMAOB | |
| SCHEMBL6337007 | 0.79 | MAOA (0.53) | MAOAMAOB | |
| SCHEMBL6715644 | 0.78 | MAOA (0.34) | GRM2MAOAMAOB | |
| SCHEMBL6336569 | 0.76 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL7070828 | 0.76 | HDAC1 (0.34) | — | |
| SCHEMBL5744820 | 0.75 | GRM2 (0.30) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |