Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CALML3 | P27482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338338 | 0.87 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6338343 | 0.87 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6337208 | 0.87 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6338342 | 0.87 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6711455 | 0.86 | CALML3 (0.35) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6711244 | 0.78 | GRM2 (0.32) | MAOAMAOBGRM2 | |
| SCHEMBL6335698 | 0.73 | MAOA (0.60) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6345385 | 0.73 | MAOA (0.60) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6345383 | 0.73 | MAOA (0.60) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6335842 | 0.73 | MAOA (0.60) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |