SCHEMBL6711713

SCHEMBL6711713

N#Cc1cc(Br)ccc1NC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALB P02768 6/20 0.73
THRB P10828 1/20 0.69
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
GAA P10253 2/20 0.59
PABPC1 P11940 1/20 0.57
APOBEC3A P31941 1/20 0.57
APOBEC3G Q9HC16 1/20 0.57
KDM4E B2RXH2 1/20 0.57
CASP1 P29466 1/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALDH1A1 P00352 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6346566 0.84 ALB (1.00) ALBKMT2AMEN1GAAALDH1A1
SCHEMBL6710318 0.83 ALB (0.74) ALBKMT2AMEN1GAAPABPC1
SCHEMBL6710460 0.80 ALB (0.78) ALBKMT2AMEN1GAAPABPC1
SCHEMBL6710466 0.80 ALB (0.78) ALBKMT2AMEN1GAAPABPC1
SCHEMBL6353328 0.80 ALB (0.81) ALBTHRBKMT2AMEN1GAA
SCHEMBL6707651 0.79 ALB (0.67) ALBTHRBKMT2AMEN1GAA
SCHEMBL6357224 0.78 ALB (0.66) ALBTHRBKMT2AMEN1GAA
SCHEMBL6708744 0.78 ALB (0.65) ALBKMT2AMEN1GAAPABPC1
SCHEMBL18127636 0.77 MAPT (0.56) KMT2AMEN1GAAALDH1A1
SCHEMBL6707643 0.77 ALB (0.64) ALBKMT2AMEN1GAAPABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040142981-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-07-22 US disclosed
WO-2004018461-A2 ANTIBACTERIAL BENZOIC ACID DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142981-A1 Antibacterial benzoic acid derivatives GABRD, PHB1, GABBR1 ALB 1298/4885THRB 4472/4885KMT2A 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.