Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842149 | 0.91 | ALDH1A1 (0.70) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL5200637 | 0.83 | CYP3A4 (0.50) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL190550 | 0.78 | TDP1 (0.72) | ALDH1A1TDP1TSHRSMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL9438398 | 0.77 | TDP1 (0.69) | ALDH1A1TDP1TSHRSMN1; SMN2POLB | |
| SCHEMBL181041 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL7291481 | 0.74 | ALDH1A1 (0.72) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL6205360 | 0.74 | TDP1 (0.64) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL14641737 | 0.73 | TDP1 (0.69) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL10959778 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL6130889 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248923-A1 | Novel 4-anilinoquinoline-3-carboxamides | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248923-A1 | Novel 4-anilinoquinoline-3-carboxamides | JAK3, JAK2, JAK1 | ALDH1A1 2836/4885HPGD 3742/4885TDP1 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.