Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | KIF5B | P33176 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708504 | 0.96 | PDPK1 (0.50) | EHMT2EHMT1PDPK1CHEK1KIT | |
| SCHEMBL6708414 | 0.89 | EHMT2 (0.49) | EHMT2EHMT1PDPK1CHEK1KDM4E | |
| SCHEMBL6707527 | 0.88 | EHMT2 (0.48) | EHMT2EHMT1PDPK1CHEK1KDR | |
| SCHEMBL6706908 | 0.84 | KDM4E (0.47) | EHMT2EHMT1PDPK1KDM4ERET | |
| SCHEMBL6710222 | 0.84 | KDM4E (0.44) | EHMT2EHMT1KDM4EALDH1A1MAPT | |
| SCHEMBL3284976 | 0.75 | LMNA (0.55) | EHMT2EHMT1HDAC1AXLKDM4E | |
| SCHEMBL5502433 | 0.75 | LMNA (0.55) | EHMT2EHMT1HDAC1AXLKDM4E | |
| SCHEMBL6707513 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1MAPT | |
| SCHEMBL6708597 | 0.72 | KDM4E (0.57) | PDPK1KDRKDM4EAURKAALDH1A1 | |
| SCHEMBL6707006 | 0.72 | KDM4E (0.57) | PDPK1KDRKDM4EAURKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248923-A1 | Novel 4-anilinoquinoline-3-carboxamides | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | US | claimed |
| US-20040248923-A1 | Novel 4-anilinoquinoline-3-carboxamides | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248923-A1 | Novel 4-anilinoquinoline-3-carboxamides | JAK3, JAK2, JAK1 | EHMT2 3232/4885EHMT1 3814/4885PDPK1 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.